**Only 7% of everyone responds as Normal to all drugs**. YOU will likely not receive the right medicines unless You and your healthcare professionals know your personal genetic responses to drugs. **People also respond to Medical Cannabinoids differently based on their gene variants.** **How Americans Respond to Rx:** - 93% do not respond "as a normal metabolizer" to Rx drugs - 75% do not respond to cancer Rx drugs - 75% of all doctor visits involve Rx drug therapy - 73% of all ER hospital visits involve Rx drug therapy - 70% of people take Rx drugs - 55% of all pain Rx drugs are ineffective - 50% do not respond to arthritis Rx drugs - 49% take at least one Rx drug in past 30 days - 48% do not respond to migraine Rx drugs - 43% do not respond to diabetes Rx drugs - 38% do not respond to depression Rx drugs - 29% take at least 5 Rx drugs - 20% do not fill their Rx drug prescriptions when their doctor first prescribes their medication - 19% of women ages 50 - 64 take antidepressant Rx drugs - 13% of overall population take antidepressant Rx drugs - $213B could be saved in healthcare costs by reducing medication overuse, underuse and other flaws in care that cause complications that can create longer & more-expensive treatments - Patient out-of-pocket costs have increased double digits each year for past several years - Most commonly prescribed Rx drugs are used for medical conditions with gastointestinal problems followed by those with behavoiral issues - Over 75% of people who use medcial Cannabis( MMJ) do so because of pain - 125,000 deaths a year and 10% of all ER hospitalizations are caused by failure by patients to follow Rx prescriptions **Medication non-adherence** can have a number of causes: patients don’t like side effects, or their lack of symptoms makes them believe they don’t need Rx drugs anymore; find it difficult to take Rx, as those to prevent recurrence of cancers—for years on end when they don’t have any proof they’re working; some simply forget. While all of these are factors, the biggest reason people don’t take their medications is $ cost! **How Americans Respond to MMJ:** You may respond to Medical Cannabis differently than other people... just like you may respond differently each prescription medication. Drug Inhibiotrs can play a huge role in determining the effectiveness of MMJ and for the Rx prescription drugs you may take.