Personalized Medicine & Pharmacogenomics

A mixture of Videos, Infographics, Personalized Medicine & Pharmacogenomics (PGx)

Personalized Medicine Articles

  • "All About Pharmacogenomics"

    • Importance of Personalized Medicine & its role in the Cannabis Industry

      **The Importance of Personalized Medicine and Its Role in the Cannabis Industry:: by Nicco Reggente March 17,2016
      Medical Jane

      • 93% of Us Have Multiple Gene Variants

        MOST OF US ARE NOT “NORMAL”… PGx testing leads to truly Personalized Medicine

        Evidenced-based data proves most of us are not normal when it comes to drug metabolism due to our personal genetics.

        In a recent analysis published in the American Journal of Health-Systems Pharmacy (April 2015) , the authors found that only 7% of over 14,000 patients tested were normal metabolizers for all five of the main drug metabolizing enzyme pathways (i.e., CYP2D6, CYP2C19, CYP2C9, CYP3A4 and CYP3A5). The other 93% of patients had at least one ‘abnormal’ or ‘at-risk’ phenotype.

        Pharmacogenetic testing for the CYP450 drug-metabolizing enzymes has been available for decades, albeit grossly underutilized.

        Due to the high prevalence of abnormal phenotypes of the five main drug metabolizing enzymes which are responsible for breaking down the majority of medications in the liver, the authors suggest that routine pharmacogenetic testing makes sense in all patients.

        Abnormal phenotypes range from Poor Metabolizers to Ultra Rapid Metabolizers. The clinical repercussions of these abnormal phenotypes include potential intolerances, early discontinuations, toxicities and treatment failures.

        Perhaps more important to note is that patients with these at-risk phenotypes “may require dose modifications or use of alternative medications”.

        Fortunately, utilizing (PGx) pharmacogenetic testing, we have a way to prevent some of these repercussions from occurring.

        • Precision Medicine Infographic (now "All About Us")


          • Precision Medicine Initiative for 1 Million People

            Read about the USA’s Precision Medicine Initiative with over 1 million pharmacogenetic tests to be completed in 2018. This initiative was recently renamed “All About Us

            Please click the title for a link to this important article!

            • Precision Medicine Video

              • Pharmcogenomics will save $Billions

                “The FDA estimates that PGx pharmacogenomic testing will save the healthcare industry $136+ Billion annually.”

                • Ethics and Personalized Medicine

                  Ethical Dilemmas of Personalized Medicine by Kelley Yuan February 7, 2018

                  With the rise of cheap and rapid gene sequencing techniques, personalized medicine has taken the spotlight in discussions about health care of the future. Personalized medicine describes the tailoring of medical treatment to fit the individual characteristics of each patient. It takes into account a patient’s specific gene profile or a distinctive set of biomarkers he expresses. Doctors can use the patient’s individual biological data to personalize his treatment plan.